| Title | Dendritic plateau generation model in cortical pyramidal neurons: A link to cortical ensembles |
| Publication Type | Conference Paper |
| Year of Publication | 2017 |
| Authors | Gao, P., Graham J. W., Angulo S., Dura-Bernal S., Lytton WW., & Antic S. D. |
| Conference Name | Society for Neuroscience 2017 (SFN '17) |
| Keywords | SFN, Society for Neuroscience |
| Abstract | Synaptic and glutamatergic inputs to the basal dendrites of cortical pyramidal neurons activate NMDA and AMPA receptors which can bring the dendrites into a long-lasting depolarized state which can spread into the soma. The resulting plateau potentials increase the excitability of the neuron by bringing membrane potential closer to threshold and reducing membrane time constant. |