|Title||Modeling electrodiffusion with the NEURON reaction-diffusion module|
|Publication Type||Conference Paper|
|Year of Publication||2017|
|Authors||Newton, A., Mcdougal R. A., Hines M. L., Miyazaki K., Ross W. N., & Lytton WW.|
|Conference Name||Society for Neuroscience 2017 (SFN '17)|
|Keywords||SFN, Society for Neuroscience|
The NEURON simulation platform is widely used by both theoretical and experimental neuroscientists, it is featured in over 1800 publications. Traditionally the simulator focused on electrophysiology, but the introduction of the reaction-diffusion module (NRxD) has allowed models to probe intracellular calcium dynamics in dystonia, extracellular potassium in spreading depression and persistent neuronal activity via ligand-gated ion channels.